Ünal, MuratÖztürk, LeventÖztürk, ÇağatayKabal, A.2019-06-272019-06-272003170307-77720307-7772https://hdl.handle.net/20.500.12469/186https://doi.org/10.1046/j.1365-2273.2003.00672.xWe investigated the seroprevalence of Helicobacter pylori in patients with obstructive sleep apnoea. A prospective clinical study consisting of 19 patients aged 23-72 years with confirmed obstructive sleep apnoea by overnight polysomnography and 36 control subjects aged 25-61 years with no history of obstructive sleep apnoea and gastroesophageal reflux complaints was conducted. Titres of serum H. pylori IgG antibody were assayed by a serum enzyme-linked immunoabsorbant assay. The difference between the study and control groups was analysed by chi-squared test. Seventeen of the 19 patients (89.5%) were found to be H. pylori positive. However 21 of the 36 control subjects (58.3%) were H. pylori positive. The seropositivity of H. pylori in obstructive sleep apnoea patients was found to be significantly higher than the control group (P = 0.017). The result of our study shows that there is a high association between H. pylori infection and obstructive sleep apnoea. This data may be important for future treatment strategies of the disease.eninfo:eu-repo/semantics/openAccessHelicobacter pyloriObstructive sleep apnoeaGastroesophageal refluxSerological testsArticle100102228WOS:00018204060000710.1046/j.1365-2273.2003.00672.x2-s2.0-034636717912680826