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Browsing Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed by Author "Abubaker, Salahaddin"

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    Article
    Citation Count: 15
    Biomarkers of Secondhand Smoke Exposure in Waterpipe Tobacco Venue Employees in Istanbul Moscow and Cairo
    (Oxford University Press, 2018) Çarkoğlu, Aslı; Rule, Ana M.; Magid, Hoda; Ferguson, Jacqueline; Susan, Jolie; Sun, Zhuolu; Torrey, Christine; Abubaker, Salahaddin; Levshin, Vladimir; Çarkoğlu, Aslı; Radwan, Ghada Nasr; El-Rabbat, Maha; Cohen, Joanna E.; Strickland, Paul; Breysse, Patrick N.; Navas-Acien, Ana
    Background: Most smoke-free legislation to reduce secondhand smoke (SHS) exposure exempts waterpipe (hookah) smoking venues. Few studies have examined SHS exposure in waterpipe venues and their employees. Methods: We surveyed 276 employees of 46 waterpipe tobacco venues in Istanbul Moscow and Cairo. We interviewed venue managers and employees and collected biological samples from employees to measure exhaled carbon monoxide (CO) hair nicotine saliva cotinine urine cotinine urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and urine 1-hydroxypyrene glucuronide (1-OHPG). We estimated adjusted geometric mean ratios (GMR) of each SHS biomarker by employee characteristics and indoor air SHS measures. Results: There were 73 nonsmoking employees and 203 current smokers of cigarettes or waterpipe. In nonsmokers the median (interquartile) range concentrations of SHS biomarkers were 1.1 (0.2 40.9) mu g/g creatinine urine cotinine 5.5 (2 15) ng/mL saliva cotinine 0.95 (0.36 5.02) ng/mg hair nicotine 1.48 (0.98 3.97) pg/mg creatinine urine NNAL 0.54 (0.25 0.97) pmol/mg creatinine urine 1-OHPG and 1.67 (1.33 2.33) ppm exhaled CO. An 8-hour increase in work hours was associated with higher urine cotinine (GMR: 1.68 95% CI: 1.20 2.37) and hair nicotine (GMR: 1.22 95% CI: 1.05 1.43). Lighting waterpipes was associated with higher saliva cotinine (GMR: 2.83 95% CI: 1.05 7.62). Conclusions: Nonsmoking employees of waterpipe tobacco venues were exposed to high levels of SHS including measurable levels of carcinogenic biomarkers (tobacco-specific nitrosamines and PAHs).
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    Article
    Citation Count: 21
    Secondhand smoke in waterpipe tobacco venues in Istanbul Moscow and Cairo
    (Academic Press Inc Elsevier Science, 2019) Çarkoğlu, Aslı; Magid, Hoda; Torrey, Christine; Rule, Ana M.; Ferguson, Jacqueline; Susan, Jolie; Sun, Zhuolu; Abubaker, Salahaddin; Levshin, Vladimir; Çarkoğlu, Aslı; Radwan, Ghada Nasr; El-Rabbat, Maha; Cohen, Joanna E.; Strickland, Paul; Navas-Acien, Ana; Breysse, Patrick N.
    Objective: The prevalence of waterpipe tobacco smoking has risen in recent decades. Controlled studies suggest that waterpipe secondhand smoke (SHS) contains similar or greater quantities of toxicants than cigarette SHS which causes significant morbidity and mortality. Few studies have examined SHS from waterpipe tobacco in real-world settings. The purpose of this study was to quantify SHS exposure levels and describe the characteristics of waterpipe tobacco venues. Methods: In 2012-2014 we conducted cross-sectional surveys of 46 waterpipe tobacco venues (9 in Istanbul 17 in Moscow and 20 in Cairo). We administered venue questionnaires conducted venue observations and sampled indoor air particulate matter (PM2.5) (N=35) carbon monoxide (CO) (N=23) particle-bound polycyclic aromatic hydrocarbons (p-PAHs) (N=31) 4-methylnitrosamino)-1-(3-pyridy1)-1-butanone (NNK) (N-43) and air nicotine (N=46). Results: Venue characteristics and SHS concentrations were highly variable within and between cities. Overall we observed a mean (standard deviation (SD)) of 5 (5) waterpipe smokers and 5 (3) cigarette smokers per venue. The overall median (25th percentile 75th percentile) of venue mean air concentrations was 136 (82 213) mu/m(3) for PM2.5 3.9 (1.7 22) ppm for CO 68 (33 121) ng/m(3) for p-PAHs 1.0 (0.5 1.9) ng/m(3) for NNK and 5.3 (0.7 14) mu g/m(3) for nicotine. PM2.5 CO and p-PAHs concentrations were generally higher in venues with more waterpipe smokers and cigarette smokers although associations were not statistically significant. Conclusion: High concentrations of SHS constituents known to cause health effects indicate that indoor air quality in waterpipe tobacco venues may adversely affect the health of employees and customers. (C) 2015 Elsevier Inc. All rights reserved.