The evaluation of microbial contamination in platelet concentrates prepared by two different methods

dc.contributor.authorKocazeybek, Bekir Sami
dc.contributor.authorArabaci, Ümit
dc.contributor.authorAkdur, Hülya
dc.contributor.authorSezgic, Metin
dc.contributor.authorErentürk, Selim
dc.date.accessioned2019-06-27T08:01:04Z
dc.date.available2019-06-27T08:01:04Z
dc.date.issued2001
dc.description.abstractThe microbial contamination of platelet concentrates (PCs) prepared by two different methods both with a high risk of bacterial contamination during preparation and storage were evaluated. For apheresis platelets the concentrates were obtained using the Haemonetics MCS 3P device. For the random method platelets were obtained by two phase centrifugation in the Heraeus Cryofuge 8500 I device using the Kansuk 3-way bags which permit storage for five days. 1620 platelet pheresis units prepared by apheresis and 9838 units prepared by the random method were included in the study. Of the 11458 PCs studied 32 (0.27%) were false positives and 24 (0.2%) were real positives. All of the positive results occurred in platelets prepared by the random method. C. xerosis and S. epidermidis S. hominis Alpha-hemolytic streptococci all flora of the skin were isolated in the contaminated concentrates. The risk of microbial contamination of PCs prepared both by apheresis and from whole blood continues at a low rate although the products were collected into specific bags following rules including appropriate disinfection of the skin correct centrifugation collection time and optimal storage conditions including temperature and agitation. These results again emphasize the importance of. obeying phlebotomy rules and hand disinfection of the person who collects the blood as well as the need for careful skin decontamination of the donor during donation. (C) 2001 Elsevier Science Ltd. All rights reserved.en_US]
dc.identifier.citation2
dc.identifier.doi10.1016/S1473-0502(01)00104-5en_US
dc.identifier.endpage112
dc.identifier.issn1473-0502en_US
dc.identifier.issn1473-0502
dc.identifier.issue2
dc.identifier.pmid11761274en_US
dc.identifier.scopus2-s2.0-0035176631en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage107en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12469/238
dc.identifier.urihttps://doi.org/10.1016/S1473-0502(01)00104-5
dc.identifier.volume25en_US
dc.identifier.wosWOS:000172400500005en_US
dc.identifier.wosqualityN/A
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.journalTransfusion and Apheresis Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe evaluation of microbial contamination in platelet concentrates prepared by two different methodsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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