Short Term Effects of a Low-Carbohydrate Diet in Overweight and Obese Subjects With Low Hdl-C Levels
Loading...
Date
2010
Authors
Can, Ahmet Selçuk
Uysal, Canan
Palaoğlu, K. Erhan
Journal Title
Journal ISSN
Volume Title
Publisher
BIOMED CENTRAL LTD
Open Access Color
OpenAIRE Downloads
OpenAIRE Views
Abstract
Background: The aim of this study was to evaluate short-term effects of a low-carbohydrate diet in overweight and obese subjects with low HDL-C levels. Methods: Overweight (BMI between 25-30 kg/m(2)) or obese (BMI over 30 kg/m(2)) subjects with low HDL-C levels (men with HDL-C < 1.03 women < 1.29 mmol/l) were invited to the study. A 1400 kcal 75-gram carbohydrate (CHO) diet was given to women and an 1800 kcal 100-gram CHO diet was given to men for four weeks. The distribution of daily energy of the prescribed diet was 21-22% from CHO 26-29% from protein and 49-53% from fat. Subjects completed a three-day dietary intake record before each visit. Anthropometric indices body fat ratio blood lipids glucose and insulin were measured. Baseline and week-four results were compared with a Wilcoxon signed ranks test. Results: Twenty-five women and 18 men participated. Basal median LDL-C level of men was 3.11 and basal median LDL-C level of women was 3.00 mmol/l. After four weeks of a low-carbohydrate diet the median energy intake decreased from 1901 to 1307 kcal/day daily energy from carbohydrate from 55% to 33% body weight from 87.7 to 83.0 kg and HDL-C increased from 0.83 to 0.96 mmol/l in men (p < 0.002 for all). After four weeks of a low-carbohydrate diet the median energy intake tended to decrease (from 1463 to 1243 kcal p = 0.052) daily energy from carbohydrate decreased from 53% to 30% (p < 0.001) and body weight decreased from 73.2 to 70.8 kg (p < 0.001) in women but HDL-C did not significantly change (from 1.03 to 1.01 mmol/l p = 0.165). There were significant decreases in body mass index waist circumference body fat ratio systolic blood pressure total cholesterol triglyceride and insulin levels in all subjects. Conclusions: HDL-C levels increased significantly with energy restriction carbohydrate restriction and weight loss in men. HDL-C levels didn't change in women in whom there was no significant energy restriction but a significant carbohydrate restriction and a relatively small but significant weight loss. Our results suggest that both energy and carbohydrate restriction should be considered in overweight and obese subjects with low HDL-C levels especially when LDL-C levels are not elevated.
Description
Keywords
Turkish CoHE Thesis Center URL
Fields of Science
Citation
WoS Q
Scopus Q
Q2
Source
Volume
10