A new lung cancer detection method based on the chest CT images using Federated Learning and blockchain systems

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Date

2023

Authors

Heidari, Arash
Javaheri, Danial
Toumaj, Shiva
Navimipour, Nima Jafari
Rezaei, Mahsa
Unal, Mehmet

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Open Access Color

Green Open Access

No

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Publicly Funded

No
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Top 1%
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Top 10%
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Top 1%

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Abstract

With an estimated five million fatal cases each year, lung cancer is one of the significant causes of death worldwide. Lung diseases can be diagnosed with a Computed Tomography (CT) scan. The scarcity and trustworthiness of human eyes is the fundamental issue in diagnosing lung cancer patients. The main goal of this study is to detect malignant lung nodules in a CT scan of the lungs and categorize lung cancer according to severity. In this work, cutting-edge Deep Learning (DL) algorithms were used to detect the location of cancerous nodules. Also, the real-life issue is sharing data with hospitals around the world while bearing in mind the organizations' privacy issues. Besides, the main problems for training a global DL model are creating a collaborative model and maintaining privacy. This study presented an approach that takes a modest amount of data from multiple hospitals and uses blockchain-based Federated Learning (FL) to train a global DL model. The data were authenticated using blockchain technology, and FL trained the model internationally while maintaining the organization's anonymity. First, we presented a data normalization approach that addresses the variability of data obtained from various institutions using various CT scanners. Furthermore, using a CapsNets method, we classified lung cancer patients in local mode. Finally, we devised a way to train a global model cooperatively utilizing blockchain technology and FL while maintaining anonymity. We also gathered data from real-life lung cancer patients for testing purposes. The suggested method was trained and tested on the Cancer Imaging Archive (CIA) dataset, Kaggle Data Science Bowl (KDSB), LUNA 16, and the local dataset. Finally, we performed extensive experiments with Python and its well-known libraries, such as Scikit-Learn and TensorFlow, to evaluate the suggested method. The findings showed that the method effectively detects lung cancer patients. The technique delivered 99.69 % accuracy with the smallest possible categorization error.

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Keywords

Blockchain, Chest CT, CapsNets, Profile, Deep Learning, Federated Learning, Profile, Lung cancer, Chest CT, Deep Learning, Blockchain, Lung Neoplasms, CapsNets, Data Science, Humans, Profile, Lung cancer, Tomography, X-Ray Computed, Federated Learning, Algorithms

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WoS Q

Q1

Scopus Q

Q1
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OpenCitations Citation Count
62

Source

Artificial Intelligence in Medicine

Volume

141

Issue

Start Page

102572

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Citations

Scopus : 111

PubMed : 19

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Mendeley Readers : 126

SCOPUS™ Citations

114

checked on Feb 06, 2026

Web of Science™ Citations

84

checked on Feb 06, 2026

Page Views

10

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34.30510114

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