In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With Gsk3-Β Protein
| dc.contributor.author | Aksoy, Halil | |
| dc.contributor.author | Şekerler, Turgut | |
| dc.contributor.author | Mert, Naz Mina | |
| dc.date.accessioned | 2024-10-15T19:43:02Z | |
| dc.date.available | 2024-10-15T19:43:02Z | |
| dc.date.issued | 2021 | |
| dc.description.abstract | Wound healing is a process that involves biochemical processes such as inflammation and cell proliferation and is controlled by many proteins. It is known that one of the most effective factors in this process is the inhibition of GSK3-β protein. In current study, in silico wound healing activity of the some compounds found in the tubers of Asphodelus species used as a wound healing in traditional medicine were investigated. For this purpose, the interactions between the compounds and GSK3-β protein were studied in silico. As a result of the study, it has been determined that and stigmasterol, β-sitosterol and emodin molecules are effective. | en_US |
| dc.identifier.doi | 10.29228/jrp.65 | |
| dc.identifier.issn | 2630-6344 | |
| dc.identifier.uri | https://doi.org/10.29228/jrp.65 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/en/yayin/detay/489776/in-silico-investigation-of-wound-healing-potential-of-some-compounds-in-tubers-of-asphodelus-species-with-gsk3-b-protein | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12469/6624 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/en/yayin/detay/489776 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Journal of research in pharmacy (online) | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Biyoloji | |
| dc.title | In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With Gsk3-Β Protein | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.author.id | 0000-0002-8858-4500 | |
| gdc.author.id | 0000-0002-7256-0037 | |
| gdc.author.id | 0000-0002-3120-2911 | |
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| gdc.coar.access | open access | |
| gdc.coar.type | text::journal::journal article | |
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| gdc.description.department | Kadir Has University | en_US |
| gdc.description.departmenttemp | MARMARA ÜNİVERSİTESİ,MARMARA ÜNİVERSİTESİ,KADİR HAS ÜNİVERSİTESİ | en_US |
| gdc.description.endpage | 754 | en_US |
| gdc.description.issue | 5 | en_US |
| gdc.description.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.scopusquality | Q4 | |
| gdc.description.startpage | 747 | en_US |
| gdc.description.volume | 25 | en_US |
| gdc.description.wosquality | Q4 | |
| gdc.identifier.openalex | W3200979195 | |
| gdc.identifier.trdizinid | 489776 | |
| gdc.index.type | TR-Dizin | |
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| gdc.oaire.keywords | Eczacılık Biyokimyası | |
| gdc.oaire.keywords | GSK3-beta protein | |
| gdc.oaire.keywords | Glycogen-Synthase Kinase-3-Beta | |
| gdc.oaire.keywords | Asphodelus species;β-sitosterol;emodin;GSK3-β protein;stigmasterol;wound healing activity | |
| gdc.oaire.keywords | wound healing activity | |
| gdc.oaire.keywords | Docking | |
| gdc.oaire.keywords | emodin | |
| gdc.oaire.keywords | Pharmaceutical Biochemistry | |
| gdc.oaire.keywords | stigmasterol | |
| gdc.oaire.keywords | GLYCOGEN-SYNTHASE KINASE-3-BETA | |
| gdc.oaire.keywords | Asphodelus species | |
| gdc.oaire.keywords | DOCKING | |
| gdc.oaire.keywords | beta-sitosterol | |
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