The seroprevalence of Helicobacter pylori infection in patients with obstructive sleep apnoea: a preliminary study

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Date

2003

Authors

Ünal, Murat
Öztürk, Levent
Öztürk, Çağatay
Kabal, A.

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Publisher

Blackwell Publishing Ltd

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Abstract

We investigated the seroprevalence of Helicobacter pylori in patients with obstructive sleep apnoea. A prospective clinical study consisting of 19 patients aged 23-72 years with confirmed obstructive sleep apnoea by overnight polysomnography and 36 control subjects aged 25-61 years with no history of obstructive sleep apnoea and gastroesophageal reflux complaints was conducted. Titres of serum H. pylori IgG antibody were assayed by a serum enzyme-linked immunoabsorbant assay. The difference between the study and control groups was analysed by chi-squared test. Seventeen of the 19 patients (89.5%) were found to be H. pylori positive. However 21 of the 36 control subjects (58.3%) were H. pylori positive. The seropositivity of H. pylori in obstructive sleep apnoea patients was found to be significantly higher than the control group (P = 0.017). The result of our study shows that there is a high association between H. pylori infection and obstructive sleep apnoea. This data may be important for future treatment strategies of the disease.

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Keywords

Helicobacter pylori, Obstructive sleep apnoea, Gastroesophageal reflux, Serological tests

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Citation

17

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N/A

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N/A

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Volume

28

Issue

2

Start Page

100

End Page

102