Antihepatitis B response to hepatitis B vaccine administered simultaneously with tetanus toxoid in nonresponder individuals
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Date
2002
Authors
Sönmez, Emine
Sönmez, Ali Suha
Bayındır, Yaşar
Coşkun, Diler
Ariturk, Sedat
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Science
Abstract
In this prospective study our aim was to test the effect of simultaneous administration of preS2 and S containing recombinant hepatitis B vaccine (S2SRHB) with tetanus toxoid (TT) to the individuals who did not respond after three doses of hepatitis B vaccine previously. There were three groups (healthy individuals pregnant women hemodialysis patients) each was divided into two subgroups as groups A and B. Group A received S2SRHB + TT and group B received only S2SRHB. We found that in groups receiving both vaccines both seroconversion rate and antibody titer level were significantly higher (P < 0.05). In conclusion simultaneous administration of S2SRHB + TT is more effective than administration of S2SRHB alone. (C) 2002 Elsevier Science Ltd. All rights reserved.
Description
Keywords
Hepatitis B vaccine, Tetanus toxoid, Nonresponder
Turkish CoHE Thesis Center URL
Citation
10
WoS Q
Q3
Scopus Q
Q1
Source
Volume
21
Issue
Start Page
243
End Page
246