Hydrogels From Protein-Polymer Conjugates: a Pathway To Next-Generation Biomaterials
dc.authorid | Poyraz, Yagmur/0000-0002-5318-7978 | |
dc.authorscopusid | 59386008400 | |
dc.authorscopusid | 59385393300 | |
dc.authorscopusid | 58986629200 | |
dc.authorscopusid | 57736023600 | |
dc.authorscopusid | 59660454800 | |
dc.authorscopusid | 59661154200 | |
dc.authorscopusid | 6507297154 | |
dc.authorwosid | Akten, Ebru/Aag-7752-2019 | |
dc.authorwosid | Uysal, Bengü/G-9131-2019 | |
dc.authorwosid | Poyraz, Yağmur/Mik-5504-2025 | |
dc.contributor.author | Alayoubi, Oubadah | |
dc.contributor.author | Poyraz, Yagmur | |
dc.contributor.author | Hassan, Gana | |
dc.contributor.author | Gul, Sumeyye Berfin | |
dc.contributor.author | Calhan, Nergiz | |
dc.contributor.author | Mert Sahin, Naz Mina | |
dc.contributor.author | Pekcan, Onder | |
dc.date.accessioned | 2025-03-15T20:07:03Z | |
dc.date.available | 2025-03-15T20:07:03Z | |
dc.date.issued | 2025 | |
dc.department | Kadir Has University | en_US |
dc.department-temp | [Alayoubi, Oubadah; Hassan, Gana; Gul, Sumeyye Berfin; Calhan, Nergiz; Kutlu, Aylin] Kadir Has Univ, Sch Grad Studies, Mat Sci & Nanotechnol, TR-34083 Istanbul, Turkiye; [Poyraz, Yagmur; Mert Sahin, Naz Mina; Gautam, Megha] Kadir Has Univ, Sch Grad Studies, Computat Sci & Engn, TR-34083 Istanbul, Turkiye; [Uysal, Bengu Ozugur] Altinbas Univ, Fac Engn & Architecture, Dept Basic Sci, TR-34218 Istanbul, Turkiye; [Akten, Ebru Demet; Pekcan, Onder] Kadir Has Univ, Fac Engn & Nat Sci, TR-34083 Istanbul, Turkiye | en_US |
dc.description | Poyraz, Yagmur/0000-0002-5318-7978 | en_US |
dc.description.abstract | Hybrid hydrogels from protein-polymer conjugates are biomaterials formed via the chemical bonding of a protein molecule with a polymer molecule. Protein-polymer conjugates offer a variety of biological properties by combining the mechanical strength of polymers and the bioactive functionality of proteins. These properties allow these conjugates to be used as biocompatible components in biomedical applications. Protein-polymer conjugation is a vital bioengineering strategy in many fields, such as drug delivery, tissue engineering, and cancer therapy. Protein-polymer conjugations aim to create materials with new and unique properties by combining the properties of different molecular components. There are various ways of creating protein-polymer conjugates. PEGylation is one of the most common conjugation techniques where a protein is conjugated with Polyethylene Glycol. However, some limitations of PEGylation (like polydispersity and low biodegradability) have prompted researchers to devise novel synthesis techniques like PEGylation, where synthetic polypeptides are used as the polymer component. This review will illustrate the properties of protein-polymer conjugates, their synthesis methods, and their various biomedical applications. | en_US |
dc.description.sponsorship | Personal Research Funds of Onder Pekcan | en_US |
dc.description.sponsorship | Personal Research Funds of Onder Pekcan funded this research at Kadir Has University. | en_US |
dc.description.woscitationindex | Science Citation Index Expanded | |
dc.identifier.doi | 10.3390/gels11020096 | |
dc.identifier.issn | 2310-2861 | |
dc.identifier.issue | 2 | en_US |
dc.identifier.pmid | 39996639 | |
dc.identifier.scopus | 2-s2.0-85219170336 | |
dc.identifier.scopusquality | Q3 | |
dc.identifier.uri | https://doi.org/10.3390/gels11020096 | |
dc.identifier.volume | 11 | en_US |
dc.identifier.wos | WOS:001431888900001 | |
dc.identifier.wosquality | Q1 | |
dc.language.iso | en | en_US |
dc.publisher | Mdpi | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Hybrid Hydrogels | en_US |
dc.subject | Protein-Polymer Conjugates | en_US |
dc.subject | Pegylation | en_US |
dc.title | Hydrogels From Protein-Polymer Conjugates: a Pathway To Next-Generation Biomaterials | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication |