Establishment of reference intervals of laboratory tests using hospital patient data

dc.contributor.authorToprakçı, Mustafa
dc.contributor.authorEmerk, Kaya
dc.date.accessioned2020-09-29T11:28:56Zen_US
dc.date.available2020-09-29T11:28:56Zen_US
dc.date.issued2002en_US
dc.description.abstractObjective: In this study, hospital patient data was used to derive reference intervals for selected clinical laboratory tests. Methods: Data were obtained indirectly using our hospital database including both sexes. No selection criteria have been applied. The data has been partitioned into only three age groups as, 3-20, 21-60 and 61 to older in order to prevent age related grouping in the distribution. The distributions have been checked by normality analysis using Kolmogorov-Smirnov test. Nonparametric percentile estimate method was used to obtain reference intervals in the age groups of 21-60 and 61 to older. In age group 3- 20, the number of data were below 120 in most tests so, GraphROC for Windows, a statistical package which performs a robust modified nonparametric method, was used to find reference intervals. Results: Most of the test data did not show Gaussian distribution form and parametric analysis of these data has failed. Instead, nonparametric analysis has succeeded in establishing the intervals in three age groups. Conclusion: The results resembled the characteristics of our hospital patient population. Especially, protein and lipid parameters showed clear differences in our population, compared to the reference values of the manufacturer, which are currently used. This study has been a clear evidence indicating the importance of determination of reference intervals and the analysis of indirectly selected hospital patient data using nonparametric statistical techniques.en_US
dc.identifier.citation0
dc.identifier.endpage96en_US
dc.identifier.issn1019-1941en_US
dc.identifier.issn1309-9469en_US
dc.identifier.issn1019-1941
dc.identifier.issn1309-9469
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0036556798en_US
dc.identifier.scopusqualityQ4
dc.identifier.startpage92en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12469/3458
dc.identifier.urihttps://dergipark.org.tr/tr/pub/marumj/issue/25800/272102
dc.identifier.volume15en_US
dc.identifier.wosqualityN/A
dc.institutionauthorToprakçı, Mustafaen_US
dc.language.isoenen_US
dc.publisherMarmara Üniversitesi Yayınevien_US
dc.relation.journalMarmara Medical Journalen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectReference intervalen_US
dc.subjectHospital patient dataen_US
dc.subjectNonparametricen_US
dc.titleEstablishment of reference intervals of laboratory tests using hospital patient dataen_US
dc.typeOtheren_US
dspace.entity.typePublication

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