Novel Mutants of the Aubergine Gene

dc.contributor.authorŞahin, H. Bahar
dc.contributor.authorKarataş, Ömer Faruk
dc.contributor.authorSpecchia, Valeria
dc.contributor.authorDi Tommaso, Silvia D.
dc.contributor.authorDiebold, Celine
dc.contributor.authorBozzetti, Maria Pia
dc.contributor.authorGiangrande, Angela
dc.date.accessioned2019-06-27T08:02:02Z
dc.date.available2019-06-27T08:02:02Z
dc.date.issued2016
dc.departmentFakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Biyoinformatik ve Genetik Bölümüen_US
dc.description.abstractAubergine is an RNA-binding protein of the Piwi clade functioning in germline in the piRNA pathway that silences transposons and repetitive sequences. Several mutations of this gene exist but they mostly result in truncated proteins or correspond to mutations that also affect neighboring genes. We have generated complete aubergine knock-out mutants that do not disrupt the neighboring genes. These novel mutants are characterized by PCR and sequencing. Their nature is confirmed by female sterility and by the presence of crystals in testes common to the aubergine loss of function mutations. These mutants provide novel and more appropriate tools for the study of the piRNA pathway that controls genome stability.en_US]
dc.identifier.citation6
dc.identifier.doi10.1080/19336934.2016.1174355en_US
dc.identifier.endpage90
dc.identifier.issn1933-6934en_US
dc.identifier.issn1933-6942en_US
dc.identifier.issn1933-6934
dc.identifier.issn1933-6942
dc.identifier.issue2
dc.identifier.pmid27064345en_US
dc.identifier.scopus2-s2.0-84975801480en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage81en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12469/535
dc.identifier.urihttps://doi.org/10.1080/19336934.2016.1174355
dc.identifier.volume10en_US
dc.identifier.wosWOS:000381309100004en_US
dc.identifier.wosqualityQ4
dc.institutionauthorŞahin, H. Baharen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.journalFlyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAubergineen_US
dc.subjectArgonauteen_US
dc.subjectCrystal-stellateen_US
dc.subjectKnockout mutanten_US
dc.subjectMutagenesisen_US
dc.subjectpiRNAen_US
dc.subjectSterilityen_US
dc.titleNovel Mutants of the Aubergine Geneen_US
dc.typeArticleen_US
dspace.entity.typePublication

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