In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With Gsk3-? Protein
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Date
2021
Authors
Aksoy, Halil
Sekerler, Turgut
Mert, Naz Mina
Journal Title
Journal ISSN
Volume Title
Publisher
Marmara Univ
Open Access Color
GOLD
Green Open Access
Yes
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Publicly Funded
No
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Impulse
Average
Influence
Average
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Average
Abstract
Wound healing is a process that involves biochemical processes such as inflammation and cell proliferation and is controlled by many proteins. It is known that one of the most effective factors in this process is the inhibition of GSK3-beta protein. In current study, in silico wound healing activity of the some compounds found in the tubers of Asphodelus species used as a wound healing in traditional medicine were investigated. For this purpose, the interactions between the compounds and GSK3-beta protein were studied in silico. As a result of the study, it has been determined that and stigmasterol, beta-sitosterol and emodin molecules are effective.
Description
Keywords
Asphodelus species, Glycogen-Synthase Kinase-3-Beta, beta-sitosterol, emodin, Glycogen-Synthase Kinase-3-Beta, GSK3-beta protein, Docking, stigmasterol, Docking, wound healing activity, Eczacılık Biyokimyası, GSK3-beta protein, Glycogen-Synthase Kinase-3-Beta, Asphodelus species;β-sitosterol;emodin;GSK3-β protein;stigmasterol;wound healing activity, wound healing activity, Docking, emodin, Pharmaceutical Biochemistry, stigmasterol, GLYCOGEN-SYNTHASE KINASE-3-BETA, Asphodelus species, DOCKING, beta-sitosterol
Fields of Science
Citation
WoS Q
Q4
Scopus Q
Q4
OpenCitations Citation Count
2
Source
Journal of Research in Pharmacy
Volume
25
Issue
5
Start Page
747
End Page
754
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Citations
CrossRef : 1
Scopus : 10
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Mendeley Readers : 15
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