In Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With Gsk3-? Protein

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dc.authorwosidşekerler, turgut/AAB-8855-2022
dc.contributor.authorAksoy, Halil
dc.contributor.authorSekerler, Turgut
dc.contributor.authorMert, Naz Mina
dc.date.accessioned2023-10-19T15:12:01Z
dc.date.available2023-10-19T15:12:01Z
dc.date.issued2021
dc.department-temp[Aksoy, Halil; Sekerler, Turgut] Marmara Univ, Fac Pharm, Dept Biochem, TR-34854 Istanbul, Turkey; [Mert, Naz Mina] Kadir Has Univ, Computat Biol & Bioinformat, TR-34083 Istanbul, Turkeyen_US
dc.description.abstractWound healing is a process that involves biochemical processes such as inflammation and cell proliferation and is controlled by many proteins. It is known that one of the most effective factors in this process is the inhibition of GSK3-beta protein. In current study, in silico wound healing activity of the some compounds found in the tubers of Asphodelus species used as a wound healing in traditional medicine were investigated. For this purpose, the interactions between the compounds and GSK3-beta protein were studied in silico. As a result of the study, it has been determined that and stigmasterol, beta-sitosterol and emodin molecules are effective.en_US
dc.identifier.citation1
dc.identifier.doi10.29228/jrp.65en_US
dc.identifier.endpage754en_US
dc.identifier.issn2630-6344
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85115804670en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage747en_US
dc.identifier.trdizinidhttps://search.trdizin.gov.tr/yayin/detay/489776en_US
dc.identifier.urihttps://doi.org/10.29228/jrp.65
dc.identifier.uri489776
dc.identifier.urihttps://hdl.handle.net/20.500.12469/5316
dc.identifier.volume25en_US
dc.identifier.wosWOS:000701782800022en_US
dc.khas20231019-WoSen_US
dc.language.isoenen_US
dc.publisherMarmara Univen_US
dc.relation.ispartofJournal of Research in Pharmacyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAsphodelus speciesen_US
dc.subjectGlycogen-Synthase Kinase-3-Beta
dc.subjectbeta-sitosterolen_US
dc.subjectemodinen_US
dc.subjectGlycogen-Synthase Kinase-3-BetaEn_Us
dc.subjectGSK3-beta proteinen_US
dc.subjectDocking
dc.subjectstigmasterolen_US
dc.subjectDockingEn_Us
dc.subjectwound healing activityen_US
dc.titleIn Silico Investigation of Wound Healing Potential of Some Compounds in Tubers of Asphodelus Species With Gsk3-? Proteinen_US
dc.typeArticleen_US
dspace.entity.typePublication

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