Effects of Vanadyl Sulfate on Liver of Streptozotocin-Induced Diabetic Rats
| gdc.relation.journal | Biological Trace Element Research | en_US |
| dc.contributor.author | Koyutürk, Meral | |
| dc.contributor.author | Tunali, Sevim | |
| dc.contributor.author | Bolkent, Şehnaz | |
| dc.contributor.author | Yanardağ, Refiye | |
| dc.contributor.other | 01. Kadir Has University | |
| dc.date.accessioned | 2019-06-27T08:00:52Z | |
| dc.date.available | 2019-06-27T08:00:52Z | |
| dc.date.issued | 2005 | |
| dc.description.abstract | The aim of this study was to investigate the microscopic and biochemical effects of vanadyl sulfate on liver tissue of normal and streptozotocin (65 mg/kg) diabetic rats. Vanadyl sulfate was administered by gavage at a dose of 100 mg/kg. Degenerative changes were observed in diabetic animals by light and transmission electron microscopes. Although there were individual differences in diabetic animals to which vanadium was given some reduction of degenerative changes were detected. After 60 d of treatment serum aspartate and alanine transaminase alkaline phosphatase blood glucose levels liver lipid peroxidation and nonenzymatic glycosylation significantly increased but liver glutathione levels significantly decreased in the diabetic group. On the other hand treatment with vanadyl sulfate reversed these effects. As a result it might be concluded that vanadyl sulfate has a protective effect on damage of liver of streptozotocin-induced diabetic rats. | en_US] |
| dc.identifier.citationcount | 41 | |
| dc.identifier.doi | 10.1385/BTER:104:3:233 | en_US |
| dc.identifier.issn | 0163-4984 | en_US |
| dc.identifier.issn | 0163-4984 | |
| dc.identifier.scopus | 2-s2.0-20444468073 | en_US |
| dc.identifier.uri | https://hdl.handle.net/20.500.12469/129 | |
| dc.identifier.uri | https://doi.org/10.1385/BTER:104:3:233 | |
| dc.language.iso | en | en_US |
| dc.publisher | Humana Press Inc. | en_US |
| dc.relation.ispartof | Biological Trace Element Research | |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.subject | Streptozotocin | en_US |
| dc.subject | Liver tissue | en_US |
| dc.subject | Vanadyl sulfate | en_US |
| dc.subject | Light microscopy | en_US |
| dc.subject | Electron microscopy | en_US |
| dc.subject | Biochemistry | en_US |
| dc.title | Effects of Vanadyl Sulfate on Liver of Streptozotocin-Induced Diabetic Rats | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| gdc.bip.impulseclass | C4 | |
| gdc.bip.influenceclass | C4 | |
| gdc.bip.popularityclass | C4 | |
| gdc.coar.access | open access | |
| gdc.coar.type | text::journal::journal article | |
| gdc.description.endpage | 247 | |
| gdc.description.issue | 3 | |
| gdc.description.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| gdc.description.startpage | 233 | en_US |
| gdc.description.volume | 104 | en_US |
| gdc.identifier.openalex | W2017526102 | |
| gdc.identifier.pmid | 15930593 | en_US |
| gdc.identifier.wos | WOS:000230354900005 | en_US |
| gdc.oaire.diamondjournal | false | |
| gdc.oaire.impulse | 9.0 | |
| gdc.oaire.influence | 4.322792E-9 | |
| gdc.oaire.isgreen | true | |
| gdc.oaire.keywords | Blood Glucose | |
| gdc.oaire.keywords | Male | |
| gdc.oaire.keywords | Glycosylation | |
| gdc.oaire.keywords | Vanadium Compounds | |
| gdc.oaire.keywords | Streptozotocin | |
| gdc.oaire.keywords | Alkaline Phosphatase | |
| gdc.oaire.keywords | Biochemistry | |
| gdc.oaire.keywords | Glutathione | |
| gdc.oaire.keywords | Diabetes Mellitus, Experimental | |
| gdc.oaire.keywords | Rats | |
| gdc.oaire.keywords | Microscopy, Electron | |
| gdc.oaire.keywords | Liver | |
| gdc.oaire.keywords | Vanadyl sulfate | |
| gdc.oaire.keywords | Electron microscopy | |
| gdc.oaire.keywords | Animals | |
| gdc.oaire.keywords | Hypoglycemic Agents | |
| gdc.oaire.keywords | Light microscopy | |
| gdc.oaire.keywords | Lipid Peroxidation | |
| gdc.oaire.keywords | Liver tissue | |
| gdc.oaire.keywords | Transaminases | |
| gdc.oaire.popularity | 8.52732E-9 | |
| gdc.oaire.publicfunded | false | |
| gdc.oaire.sciencefields | 0301 basic medicine | |
| gdc.oaire.sciencefields | 0303 health sciences | |
| gdc.oaire.sciencefields | 03 medical and health sciences | |
| gdc.openalex.fwci | 2.003 | |
| gdc.openalex.normalizedpercentile | 0.96 | |
| gdc.openalex.toppercent | TOP 10% | |
| gdc.opencitations.count | 41 | |
| gdc.plumx.crossrefcites | 24 | |
| gdc.plumx.mendeley | 18 | |
| gdc.plumx.pubmedcites | 14 | |
| gdc.plumx.scopuscites | 49 | |
| gdc.scopus.citedcount | 49 | |
| gdc.wos.citedcount | 42 | |
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